The world of vein treatments are constantly evolving, and it seems like every week there’s an exciting new discovery! Recently, Nature magazine revealed a new one: they’ve identified the stem cells responsible for growing new blood vessels in embryos. Why is that so exciting? If the cells can be studied and applied to adults, scientists could also grow healthy new blood vessels. And those vessels could repair or replace old, damaged ones.
New Veins Could Transform Circulatory Treatments
Vein disease sufferers will obviously benefit from newly-grown veins. But so will other people. In fact, this development would improve treatments for heart disease. It could also help manage circulatory conditions like peripheral arterial disease.
Until now, scientists thought that dividing endothelial cells created embryo blood vessels. But this new research proves that the opposite is true. In short, stems cells in the blood create and grow endothelial cells.
Of course, we can’t yet grow new blood vessels. So we can’t yet apply this discovery to help treat vein disease. In order for that to happen, researchers will have to determine whether the stem cells can grow endothelial cells throughout life. Because there’s a chance this only happens during the embryo stage of development.
Moving Forward with Embryo Research
Unfortunately, we don’t yet have the methods necessary to track down these tiny stem cells in fully grown humans. And, even once those methods are developed, scientists will need to determine if the endothelial cells that come from these stem cells have their own functions. They will also need to figure out the best way to apply them for use in regenerative medicine.
Even with all the work that’s left to be done, the Associate Medical Director of the British Heart Foundation, Professor Metin Avkiran, is positive about the discovery. He says, “Using stem cells to treat patients with heart and circulatory disease has huge potential. But taking positive findings from the lab to patients has often been very challenging. These scientists have looked at how blood vessels develop in the embryo, and their findings have shed important new light on our understanding of the origin of growing blood vessels. Getting these fundamentals right is essential for finding stem cell treatments which will work in patients. These findings could pave the way to new discoveries in regenerative medicine and allow scientists in the future to grow new blood vessels and repair those that are damaged in many forms of heart and circulatory disease.”
Sources: University College London, Nature Magazine